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X-WR-CALDESC:Events for KESHO
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TZID:Africa/Nairobi
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DTSTART:20240101T000000
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BEGIN:VEVENT
DTSTART;TZID=Africa/Nairobi:20250717T190000
DTEND;TZID=Africa/Nairobi:20250717T203000
DTSTAMP:20260528T014900
CREATED:20250414T201147Z
LAST-MODIFIED:20250806T114844Z
UID:24403-1752778800-1752784200@kesho-kenya.org
SUMMARY:Endometrial Cancer
DESCRIPTION:Moderator: Dr Anisa Mburu\n1. Dr. Caroline Tonio – Advanced Endometrial Cancer\nDr. Tonio’s presentation highlighted significant advancements in the treatment of advanced and recurrent endometrial cancer. With rising incidence and poor outcomes in late-stage disease\, treatment has evolved from conventional chemotherapy to biomarker-driven strategies. \nMolecular subtyping\, as identified by the TCGA\, has enabled the use of immune checkpoint inhibitors (ICIs) and targeted therapies. Notably\, ICIs like dostarlimab and pembrolizumab show strong efficacy in dMMR/MSI-H tumors. Emerging combinations of ICIs with chemotherapy or TKIs are improving survival outcomes. The integration of molecular profiling is now essential in selecting optimal therapies. Future care will increasingly rely on predictive biomarkers to guide personalized treatment. \n2. Dr. Khadija Warfa – Endometrial Cancer Pathology and Surgical Staging\nDr. Warfa provided an overview of the pathology\, risk factors\, and staging of endometrial cancer. Most cases occur in postmenopausal women\, with abnormal bleeding as a common symptom. Risk factors include estrogen exposure\, obesity\, and genetic syndromes. \nDiagnosis relies on biopsy and imaging. Pathologically\, cancers are divided into Type I and II\, with molecular subtypes (e.g.\, POLE\, dMMR\, p53-abn) offering greater prognostic value. \nStandard surgical management involves hysterectomy with lymph node assessment. Sentinel lymph node biopsy is preferred in many cases due to lower complication rates. Minimally invasive approaches offer comparable survival outcomes with reduced morbidity.
URL:https://kesho-kenya.org/event/endometrial-cancer-2/
CATEGORIES:CME 2025,Continuing Medical Education (CME)
ATTACH;FMTTYPE=image/png:https://kesho-kenya.org/wp-content/uploads/2025/04/unnamed-e1752574943250.png
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