Date: 19 June 2025 | Time: 7:00 – 8:30 PM EAT

Moderator: Dr Peter Oyiro

Prof. Jessie Githang’a – Sickle Cell Clinical Trials in Kenya

Prof. Jessie Githang’a emphasized the need for more SCD clinical trials in Africa, where the disease burden is greatest. She outlined the underrepresentation of African populations in global trials and highlighted the benefits of local research, including better understanding of drug efficacy, safety, and socio-genetic differences. She discussed ongoing and past trials in Kenya involving Hydroxyurea, Crizanlizumab, and gene therapies, noting challenges like infrastructure gaps and limited expertise. Prof. Githang’a called for improved research capacity, team collaboration, and greater engagement with trial participants.

Dr. Doreen Mutua – Management of SCD in the 21st Century

Dr. Doreen Mutua reviewed modern SCD management, highlighting the importance of early diagnosis, health maintenance, and Hydroxyurea therapy. She addressed common complications like stroke, chronic pain, and organ damage, and emphasized early intervention to prevent progression. Transition of care for adolescents, genetic counseling, and curative options such as HSCT and gene editing were also discussed. Her presentation underscored the need for advocacy, access to comprehensive care, and integration of newborn screening into national systems.